Dr. Partha Pratim Dutta

Journal Publications:

1. Saikia, L., Talukdar, N.C., Dutta, P.P.*, 2025. Exploring the Therapeutic Role of Flavonoids Through AMPK Activation in Metabolic Syndrome: A Narrative Review. Phytotherapy Research (Ahead of print) (I. F. 6.1)
2. Kalita, V., Bhattacharyya, J., Bora, S.J., Kalita, R., Dutta, P.P.* Fractionation and separation of bioactive peptides using natural polymeric membrane. Brazilian Journal of Pharmaceutical Sciences. (Manuscript accepted). (I. F. 0.6)
3. Chutia, B., Dutta, P.P., Saikia, L., Chowdhury, P., Borah, M., Barhoi, D., Kumar, R., Borah, S.N., Borah, D., Manhar, A.K. and Mandal, M., 2025. Exploring the antidiabetic activity of potential probiotic bacteria isolated from traditional fermented beverage. World Journal of Microbiology and Biotechnology, 41(1), pp.1-15. (I. F. 4.0)
4. Saikia, L., Aziz Barbhuiya, S.A., Saikia, K., Kalita, P. and Dutta, P.P.*, 2024. Therapeutic Potential of Quercetin in Diabetic Neuropathy and Retinopathy: Exploring Molecular Mechanisms. Current Topics in Medicinal Chemistry, 24(27), pp.2351-2361. (I. F. 2.9)
5. Narzary, B., Tamuli, K.J., Dutta, P.P., Bordoloi, M. and Bora, D., 2024. Oldenlandia diffusa (Willd.) Roxb. Essential Oil from Assam, India: GC-MS Analysis and Anticancer Activity: Vietnam Journal of Science and Technology, 62(5), pp.879-893.
6. Barbhuiya, A.A., Dutta, P.P.*, Barua, C.C., Saikia, K., Kakati, A. Harnessing the Therapeutic Potential of Plants and Plant-Derived Constituents in Diabetic Neuropathy: Recent Advances and Challenges. Current Drug Therapy. 2024. (I. F. 0.3)
7. Saikia, L., Gogoi, B., Sen, S., Tonk, R.K., Kumar, D., Dutta, P.P.* The recent update and advancements of natural products in targeting the Wnt/β-Catenin pathway for cancer prevention and therapeutics. Medical Oncology. 2024. 41(7), 1-18. (I. F. 2.8)
8. Saikia, L., Bhattacharyya, J., Sen, S., Dutta, P.P.*. A Review on Ethnobotany, Phytochemistry and Pharmacological activities of Euphorbia antiquorum L. Chemistry & Biodiversity. 2024. p.e202400331. (I. F. 2.3)
9. Alam, M.J., Kamboj, P., Sarkar, S., Gupta, S.K., Kasarla, S.S., Bajpai, S., Kumari, D., Bisht, N., Barge, S.R., Kashyap, B. Deka, B., Bharadwaj, S., Rahman, S., Dutta, P.P., Borah, J.C., Talukdar, N.C., Kumar, Y., Banerjee, S. Untargeted metabolomics and phenotype data indicate the therapeutic and prophylactic potential of Lysimachia candida Lindl. towards high-fat high-fructose-induced metabolic syndrome in rats. Molecular Omics. 10, 2023, 787-799  (I. F. 3.0)
10. Chelleng, N., Begum, T., Dutta, P.P., Chetia, P., Sen, S., Dey, B.K., Talukdar, N.C. and Tamuly, C., 2023. Antidiabetic potential of Amomum dealbatum Roxb. flower and isolation of three bioactive compounds with molecular docking and in vivo study. Natural Product Research, pp.1-6 (I. F. 2.2).
11. Randhoni, C. N., Gogoi, P., Barbhuiya, P.A., Dutta, P. P., Pathak, M., Sen, S. Natural Flavonoids as Potential Therapeutics in the Management of Diabetic Wound: A Review. Current Topics in Medicinal Chemistry. 2023. 23. 690-710 (I. F. 2.9).
12. Mazumdar, R., Dutta, P.P., Saikia, J., Borah, J., Thakur D. Streptomyces sp. PBR11, a forest-derived soil actinomycetia with antimicrobial potentials. Microbiology Spectrum. 2022. 11 (2) e03489-22. (I. F. 3.7).
13. Dutta, P.P., Marbaniang, K., Sen, S., Dey, B. K., Talukdar, N.C. A review on phytochemistry of Paederia foetida Linn. Phytomedicine Plus. 2023. 100411.
14. Barbhuiya, P. A., Laskar, A. M., Mazumdar, H., Dutta, P. P., Pathak, M. P., Dey, B. K., & Sen, S. Ethnomedicinal Practices and Traditional Medicinal Plants of Barak Valley, Assam: a systematic review. Journal of Pharmacopuncture, 2022. 25(3): 149-185.
15. Sarma, H., Rabha, D., Khound, P., Gurumayum, N., Sarma, P.P., Dutta, P.P., Choudhury, P., Saikia, K., Pait, S., Borah, J.C. and Barman, D., 2022. Comparative phytochemical screening through high-performance thin layer chromatography technique and free radical scavenging ability of five species of genus Clerodendrum. Vegetos, 2022: 1 -12.
16. Sen, S., Borah, P., Dutta, P.P., Chakraborty, R. Evolving spectrum of diabetic wound: Mechanistic insights and therapeutic targets. World Journal of Diabetes, 2022 13(9): 668-801 (I. F. 4.2).
17. Barge, S., Deka, B., Kashyap, B., Bharadwaj, S., Kandimalla, R., Ghosh, A., Dutta, P.P., Samanta, S.K., Manna, P., Borah, J.C. and Talukdar, N.C. Astragalin mediates the pharmacological effects of Lysimachia candida Lindl on adipogenesis via downregulating PPARG and FKBP51 signaling cascade.     Phytotherapy Research. 2021. 35: 6990-7003. (I. F. 6.1).
18. Kashyap, B., Barge, S.R., Bharadwaj, S., Deka, B., Rahman, S., Ghosh, A., Manna, P., Dutta, P.P., Sheikh, Y., Kandimalla, R., Samanta, S.K., Boruwa, J., Saikia, S., Swargiary, D., Kamboj, P., Tuli, D., Pal, U., Borah, J.C., Banerjee, S.K., Talukdar, N.C. Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade. Phytomedicine. 2021. 93: 153761. (I. F. 6.7).
19. Kamboj, P., Sarkar, S., Gupta, S. K., Bisht, N., Kumari, D., Alam, M.J., Barge, S., Kashyap, B., Deka, B., Bharadwaj, S., Rahman, S., Dutta, P.P., Borah, J.C., Talukdar N.C., Banerjee, S. K., Kumar Y. Methanolic Extract of Lysimachia Candida Lindl. Prevents High-Fat High-Fructose-Induced Fatty Liver in Rats: Understanding the Molecular Mechanism Through Untargeted Metabolomics Study. Frontiers in pharmacology. 2021;12: 653872 (I. F. 4.4).
20. Devi, J., Sharma, S., Kumar, S., Jindal, D.K., Dutta, P.P. and Kumar, D. Transition metal (II) complexes of hydrazones derived from tetralone: synthesis, spectral characterization, in vitro antimicrobial and cytotoxic studies. Research on Chemical Intermediates. 2021; 47: 2433–2467. (I. F. 2.8)
21. Devi, J., Yadav, J., Lal, K., Kumar, N., Paul, A.K., Kumar, D., Dutta, P.P., Jindal, D.K. Design, synthesis, crystal structure, molecular docking studies of some diorganotin (IV) complexes derived from the piperonylic hydrazide Schiff base ligands as cytotoxic agents. Journal of Molecular Structure. 2021. 1232, 129992. (I. F. 4.0)
22. Das, M., Kandimalla, R., Gogoi, B., Dutta, K. N., Choudhury, P., Devi, R., Dutta, P. P., Talukdar, N. C., Samanta, S. K. Mahanine, A dietary phytochemical, represses mammary tumor burden in rat and inhibits subtype regardless breast cancer progression through suppressing self-renewal of breast cancer stem cells. Pharmacological Research. 2019. 146: 104330. (I. F. 9.1)
23. Bordoloi, M., Sahoo R.K., Tamuli, K.J., Saikia, S., Dutta P. P. Plant Extracts Promoted Preparation of Silver and Gold Nanoparticles: A Systematic Review. Nano brief reports and reviews. 2020. 15: 2030001.
24. Dutta P. P., Bordoloi M., Roy S., Narzary B., Gogoi K., Bhattacharyya D. R., Mohapatra P. K., Mazumder B. Antiplasmodial activity of Gnetum gnemon L. leaves and its isolated compounds. Natural Product Communication. 2018. 13: 1263-65 (I. F. 1.496)
25. Kotoky, R., Bordoloi, M., Yadav, A., Tamuli, K.J., Saikia, S., Dutta, P.P., Khound P.P., Saikia, S.P. Chemical composition and antibacterial activity of essential oil from fruit of Micromelum integerrimum (Buch.-Ham. ex DC.) Wight & Arn. Ex M. Roem. Natural Product Research. 2018.13:1-4. (I. F. 2.2)
26. Dutta P. P., Bordoloi M., Gogoi K., Roy S., Narzary B., Bhattacharyya D. R., Mohapatra P. K., Mazumder B. Antimalarial silver and gold nanoparticles: Green synthesis, characterization and in vitro study. Biomedicine & Pharmacotherapy. 2017. 91: 567–580. (I. F. 6.9)
27. Bordoloi M., Saikia S., Bordoloi P. K., Kolita B., Dutta P. P., Bhuyan P. D., Dutta S. C., Rao P. G. Isolation, characterization and antifungal activity of very long chain alkane derivatives from Cinnamomum obtusifolium, Elaeocarpus lanceifolius and Baccaurea sapida. Journal of Molecular Structure. 2017. 1142: 200-210. (I. F. 4.0)
28. Talukdar M., Bordoloi M., Dutta P. P., Saikia S., Kolita B., Talukdar S., Nath S., Yadav A., Saikia R., Jha D. K., Bora T. C. Structure elucidation and biological activity of antibacterial compound from Micromonospora auratinigra, a soil Actinomycetes. Journal of Applied Microbiology. 2016. 121: 973-87. (I. F. 3.2)
29. Bordoloi M., Bordoloi P. K., Dutta P. P., Singh V., Nath S., Narzary B., Bhuyan P. D., Rao P. G., Barua I. C. Studies on some edible herbs: Antioxidant activity, phenolic content, mineral content and antifungal properties. Journal of Functional Foods. 2016. 23: 220–229 (I.F. 3.8)
30. Barua C. C., Patowary P., Bordoloi M. J., Dutta P. P., Dutta D. J., Purkayastha A., Barua I. C. Attenuating effect of Elsholtzia Communis (Collett & Hemsl.) Diels. on dysregulated hpa axis in stressful conditions. International Journal of Pharmacognosy and Phytochemical Research. 2016. 8: 651-658
31. Kolita B., Gogoi D., Dutta P.P., Bordoloi M., Bezbaruah R.L. Arabinosyl transferase inhibitor design against Mycobacterium tuberculosis using ligand based drug design approach. Bangladesh Journal of Pharmacology. 2014. 9: 225-229 (I.F. 1.6)
32. Saikia S., Kolita B., Dutta P.P., Dutta D.J., Neipihoi, Nath S., Bordoloi M., Quan P.M., Thuy T.T., Phuong D.L., Long P.Q. Marine steroids as potential anticancer drug candidates: In silico investigation in search of inhibitors of Bcl-2 and CDK-4/Cyclin D1. Steroids. 2015. 102:7-16. (I. F.  2.1)
33. Tamuly C., Dutta P. P., Bordoloi M., Bora J. Antifungal and antioxidant pyrrole derivative from Piper pedicellatum. Natural Product Communications. 2013. 8: 1451–1454. (I. F. 1.496)

Patent Publications:

1. Patowary, K., Rahman, S., Dutta, P.P., Mohanta, Y.K., Talukdar, N.C. Title of the Invention: Rhamnolipid Biosurfactant Coated Iron Nanoparticle: A Credible Approach Towards Potential Petroleum Hydrocarbon Remediation. (Indian Patent Application No. 202331052858 A)
2. Patowary, K., Rahman, S., Dutta, P.P., Mohanta, Y.K., Talukdar, N.C. Title of the Invention: Synthesis of Rhamnolipid Biosurfactant Coated Zinc-Oxide Nanoparticle and Its Anticancer Potential Against Human Breast Cancer Cell Lines. (Indian Patent Application No. 202331052859 A)
3. Bharadwaj, S., Kashyap, B., Barge, S.R., Deka, B., Kaushik, A., Kandimalla, R., Dutta, P.P., Banerjee, S.K., Borah, J.C., Talukdar, N.C. Title of the Invention: A Herbal Composition from Premna herbacea, Useful for Prevention of Obesity and Type 2 Diabetes and A Method for its Extraction. (PCT International Application No. PCT/IN2019/050887)
4. Barge, S.R., Kashyap, B., Deka, B., Bharadwaj, S., Saikia, S., Kandimalla, R., Dutta, P.P., Hazarika, A., Ghosh, A., Samanta, S.K., Borah J.C., Kumar, Y., Goel, R., Kumar, A., Banerjee, S.K., Talukdar, N.C. Title of the Invention: A Herbal Extract from Lysimachia candida for Treatment of Obesity and Related Hyperglycemia and a Method for its Extraction (Indian Patent Application No. 201931019887 A)
5. Bharadwaj, S., Kashyap, B., Barge, S.R., Deka, B., Kaushik, A., Kandimalla, R., Dutta, P.P., Gogoi, B., Goel, R., Kumar, A., Kumar, Y., Samanta, S.K., Boruwa, J., Banerjee, S.K., Talukdar, N.C. Title of the Invention: A Herbal Composition from Premna herbacea, Useful for Prevention of Obesity and Type 2 Diabetes and A Method for its Extraction. (Indian Patent Application No. 201831046382 A)

Book/Book Chapters:

1. Dutta, P. P. Alam, F., Dey, B. K., Tonk, R.K. Miscellany of Chromene in The Role of Chromenes in Drug Discovery and Development. Bentham Science Publishers Pte. Ltd. Singapore. ISBN No. 9789815124330, pp. 245-260.
2. Alam, F., Kemisetti, D., Sen, A. K., Mandhadi, J. R., Talluri, C., Dey, B. K., Dutta, P. P. Toxic Plants: Alarm for humans and animals in Recent Advances in Pharmaceutical Sciences, Vol. 7. Innovare Academic Sciences Pvt. Ltd., India, ISBN No. 9788195206599, pp. 323-359.
3. Das, P. J., Mandal, S., Dutta, P. P. Hands-On Guide to Human Anatomy and Physiology Practical. 2023. Purbayon Publication, Guwahati, Assam.

R & D Projects Handled:

1. PI in an in-house ADTU funded seed grant project on the topic entitled “Formulation development and therapeutic evaluation of an herbal shampoo by using outenga pulp and kolakhar” (Total 3.2 lakhs) (Ongoing, since February, 2024).
2. Co-PI in an in-house ADTU funded seed grant project on the topic entitled “Study on Physicochemical Composition and Therapeutic Potentials of Honey from North East Region of India” (Total 5 lakhs) (Ongoing, since February, 2024).
3. Co-PI in an in-house ADTU funded seed grant project on the topic entitled “Plant-assisted synthesis of nanomaterials for diabetic wound healing: design, fabrication and therapeutic evaluation” (Total 3 Lakhs) (Ongoing, since August, 2023).
4. Co-PI in ICMR, Govt. of India funded project entitled “Systematic pharmacological investigation of bioactive phytoconstituents present in medicinal plants found in the northeastern region of India against metabolic dysfunction-associated steatotic liver disease”(Total 51.28 lakhs) (Ongoing, since June, 2024)
5. PI in an in-house ADTU funded seed grant project on the topic entitled “A systematic investigation on two orchid species of sub-Himalayan region for their ameliorative effect on diabetes associated complications” (Total 5 lakhs) (Completed).
6. Co-PI in an in-house ADTU funded seed grant project on the topic entitled “Phytochemical and pharmacological studies of shoots extracts of Bambusa balcooa and Bambusa tulda” (Total 3 lakhs) (Ongoing, since March, 2022).
7. Co-PI in DST, Govt. of India funded project entitled “Strengthening ST community of Anini, Arunachal Pradesh by empowering knowledge and skills for socioeconomic development and sustainable Livelihood.” (Total 125.63 lakhs) (Ongoing, since September, 2022)
8. Co-PI in DST, Govt. of India funded project entitled “Socio-Economic Development of ST Communities through Hydro-Electric and Solar Power Generation, Integrated Farming and Mushroom Production” (Total 276.44 lakhs) (Ongoing, since December, 2022)
9. Co-PI in INTI, Malaysia seed grant project on the topic entitled “Garcinia sp. Ethnobotany: Phytochemicals and Antidiabetic Activity” (Total RM 25,000) (Ongoing, since December, 2022).
10. Received a Project from Popcorn School Furniture entitled “Synthesis and Characterization of Biosynthesized Silver Nanoparticles and their in vitro Antimicrobial and Antioxidant Activity Evaluation” (Total 80 thousand) (May, 2021).

Research Guidance:

1. Currently mentoring 4 Ph.D. scholars pursuing their doctoral degrees.
2. Successfully guided 6 scholars in completing their M. Pharm projects.

Invited Talk/ Resource Person:

1. Attended as Resource Person in the 4th National Conference on Forensic Nursing –Clinical Significance and Practice Opportunities held at Assam down town University on 28th June, 2024.
2. Delivered a talk as Resource Person in the 42 Hours Workshop cum Value Added Course on Nanotechnology (Amazing Nano 2023) held during 28th August to 1st November, 2023, organized by Department of Electronics and Communication Engineering, School of Technology, Assam Don Bosco University, Guwahati.
3. Delivered an invited talk in Virtual Symposium on “Application of Biotechnology” organized by INTI, Malaysia, on 20.09.2023.
4. Delivered a talk as Resource Person in the two day workshop on “Mastering the Art of Research: From Selection to Publication” held at Pratiksha Institute of Pharmaceutical Sciences, Guwahati on 1st – 2nd September, 2023.
5. Attended as a Research Person in National conference “Recent discoveries in medicinal and aromatic plants research and its sustainable development in North east India” at ADP College, Nagaon from 20th - 21st January, 2022 and delivered an invited talk on “Exploration of Indigenous Plant Resources of Northeast India in Search of Lead Molecules”.
6. Delivered an invited talk in National conference “Green, sustainable and evolving sciences, and 64th Annual Technical Session of Assam Science Society” on “Exploration of Therapeutic Potential and Phytochemical Investigation of Traditional Herbal Medicine of Northeast India for Metabolic Syndrome” at Cotton University, Guwahati from 28th-29th June, 2019 and delivered an invited talk on “Exploration of Indigenous Plant Resources of Northeast India in Search of Lead Molecules”.

Awarded Senior Research Fellowship from Indian Council of Medical Research, New Delhi in 2014

Award for Highest Cumulative Impact Factor for the academic year 2021-22 in Assam down town University, Guwahati.

Best Teacher Award for the academic year 2022-23 in Assam down town University, Guwahati.