Dr. Rahul Debnath

Dr. Rahul Debnath

About

Specialization:
Cancer Biology and Immunology

Qualification

Ph.D.: 2020 in cancer immunology from Department of Human Physiology, Tripura University, Suryamaninagar, Tripura, India.
M.Sc. 2014. (1st class 2nd) Human Physiology (Specialization: Immunology, Microbiology, and cell culture), Tripura University, Suryamaninagar, Tripura, India. 
B.Sc. (Honours): 2012. (1st class 1st, Gold medalist) Human Physiology, Physiology, M. B. B. College, Agartala, Tripura, India. 
HS (+2): 2009 from Umakanta Academy, Agartala, Tripura, India.
Madhyamik Examination: 2007 from Umakanta Academy, Agartala, Tripura, India. 

Personal Interest

Cooking and Traveling

Working Experience

Assistant Professor, Faculty of Paramedical Sciences, Department of Human Physiology, Assam Down Town University, Guwahati, Assam. 

Post Doctoral Associate: 2020 to 2024, Department of Dental Medicine, University of Pennsylvania, USA.

Research

Published papers:
1. Ukjin Kim #, Rahul Debnath#, JavierE. Maiz 1, Joshua Rico 2, Satrajit Sinha 3, Mario Andrés Blanco 2, Rumela Chakrabarti ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer, iScience, 27(4), 2024. #Equal contribution.
2. Zhaoxu Chen, Rahul Debnath, Ifeoma Chikelu, Jonathan X. Zhou, Kang I. Ko*. Primed inflammatory response by fibroblast subset is necessary for proper oral and cutaneous
wound healing. Molecular Oral Microbiology, 39(7886), 2023
3. Gatha Thacker, Samantha Henry#, Ajeya Nandi#, Rahul Debnath, Rumela Chakrabarti*, Immature natural killer cells promote progression of triple-negative breast cancer, Science Translational Medicine, 39(7886), 2023.
4. Kang I. Ko*, Brett P. Der Garabedian Zhaoxu Chen, Rahul Debnath, Annette Ko, Brittany N. Link, Jonathan M. Korostoff, Dana T. Graves. Distinct fibroblast progenitor subpopulation expedites regenerative mucosal healing by immunomodulation. Journal of Experimental Medicine. 39(7886), 2022.
5. Ajeya Nandi, Rahul Debnath, Anupma Nayak, Tsun Ki ToGatha Thacker, Megan Reilly, Sanjeev Gumber, Ilias Karagounis, Ning Li, Christopher J. Lengner, Malay Haldar, Alana L. Welm, Andres, M Blanco, Christoforos Thomas, Rumela Chakrabarti*, Dll1-Mediated Notch Signaling Drives Tumor Cell Cross-talk with Cancer-Associated Fibroblasts to Promote Radio resistance in Breast Cancer. Cancer Research, 39(7886), 2022.
6. Priyatosh Nath, Debabrata Majumder, Rahul Debnath, Mousumi Debnath, Surinder Singh Sekhawat, Debasish Maiti*. Immunotherapeutic potential of ethanolic olive leaves extract (EOLE) and IL-28B combination therapy in ENU induced animal model of leukemia. Cytokine, 39(7886), 2022.
7. Debabrata Majumder , Chaitali Sarkar, Rahul Debnath, Prasun Tribedi, Debasish Maiti*. Mechanistic insight into the synergism of IL-27 and IL-28B in regulation of benzo(a)pyrene-induced lung carcinogenesis associated ROS/NF-κB/NLRP3 crosstalk. Chemico Biological Interaction. 39(7886), 2022.
8. Debabrata Majumder , Rahul Debnath , Priyatosh Nath , K V Libin Kumar , Mousumi Debnath , Prosun Tribedi , Debasish Maiti. Bromelain and Olea europaea (L.) leaf extract mediated alleviation of benzo(a)pyrene induced lung cancer through Nrf2 and NFκB pathway. Environmental Science and Pollution Research, Springer 2021.
9. Debabrata Majumder, Priyatosh Nath, Rahul Debnath, Debasish Maiti. Understanding the Complicated Relationship between Antioxidants and Carcinogenesis. Journal of Biochemical and Molecular Toxicology. 39(7886), 2020.
10. Debabrata Majumder, Rahul Debnath, Debasish Maiti. IL-27 along with IL-28B ameliorates the pulmonary redox impairment, inflammation and immunosuppression in benzo(a)pyrene induced lung cancer bearing mice. Life Sciences, (260) 2020.
11. Ashish Singha, Chaitali Sarkar, Debabrata Majumder, Rahul Debnath, Manasi Saha, Debasish Maiti*. IL-15 and GM-CSF stimulated macrophages enhances phagocytic activity in ENU induced leukemic mice. Immunobiology, 39(7886), 2019.
12. Rahul Debnath, Debabrata Majumder, Priyatosh Nath, Durgadas Ghosh, Debasish Maiti. Bromelain plus peroxidase induces non- Hodgkins lymphoma progression in invivo via up regulation anti-oxidant enzymes and modulating apoptotic protein expression. Nutrition and cancer, 39(7886), 2019.
13. Debabrata Majumder, Mousumi Debnath, K.V. Libin Kumar, Priyatosh Nath, Rahul Debnath, Chaitali Sarkar, G.B.K.S. Prasad, Yogesh Kumar Verma, Debasish Maiti. Metabolic profiling and investigations on crude extract of Olea europaea L. leaves as a potential therapeutic agent against skin cancer. Journal of Functional Foods, 39(7886), 2019.
14. Rahul Debnath, Nabanita Chatterjeeb, Subhadip Das, Snehasis Mishra, Dipayan Bose, Somenath Banerjee, Sujata Das, Krishna Das Saha, Durgadas Ghosh, Debasish Maiti*. 2019. Bromelain with peroxidase from pineapple are more potent to target leukemia growth inhibition - A comparison with only bromelain. Toxicology in Vitro, (55), 2019.
15. Rahul Debnath, Debabrata Majumder, Ashish Kumar Singha, Debasish Maiti*. Bromelain Plus Peroxidase from Pineapple Induces Apoptosis Via Mitochondrial Dependent Pathway in Lymphoma Cells. International Journal Pharmaceutical Science and Research, 9(11), 2018.

Abstract Published in Proceedings
1. Rahul Debnath, Debabrata Majumder, Ashish Kr. Singha, Durgadas Ghosh and Debasish Maiti*.Bromelain plus peroxidase from pineapple protects the Dalton’s lymphoma bearing animal. 3rd -7th January 2017. Indian Science Congress Association- 2017. Sri Venkateswara University, Tirupati, A.P, India (Poster Presentation).
2. Rahul Debnath, Debabrata Majumdar. Ashish Kr. Singha1, Durgadas Ghosh2 and Debasish Maiti. Antitumor activity of bromelain and peroxidase mixture from pineapple against T cell lymphoma: An invitro study. “Recent Trends in Biodiversity Conservation and Bio-resource Utilization (RTBCBU-2017)”. 8th-9th September 2017, Women’s College, Tripura, India (Poster Presentation).
3. Rahul Debnath, Debabrata Majumder , Ashish Kr. Singha , Chaitali Sarkar , Durgadas Ghosh, Debasish Maiti*. Antitumor activity of bromelain and peroxidase mixture from pineapple against lymphoma: An invivo study. Research Conclave-2018. 8th- 11th march, 2018. IIT Guwahati, Assam, India (Poster Presentation).
4. Rahul Debnath, Zhaoxu Chen, Kang I Ko*. Age-Dependent Upregulation of Chemokine Ccl11 in Skin Fibroblasts Is Essential for Homeostatic Subcutaneous Adipogenesis. SBDRC Scientific Symposium and Trainee Retreat, March 9, 2023, Department of Dermatology, University of Pennsylvania, USA (Poster Presentation).
5. Rahul Debnath, Zhaoxu Chen, Kang Ko. Perinatal Upregulation Of Ccl11 In Skin Fibroblasts Is Essential For Subcutaneous Adipogenesis And Wound Healing. Wound healing society annual meeting, May14-May17, 2024. Orlando Florida, USA (Junior Investigator competition, oral presentation).

Awards & Achievements

Junior investigator award in the Wound healing society annual meeting, May14-May17, 2024. Orlando Florida, USA

Best poster presentation award in the Recent Trends in Biodiversity Conservation and Bio-resource Utilization (RTBCBU-2017)”. 8th-9th September 2017, Women’s College, Tripura, India

Awarded Dr. B.R. Ambedkar Memorial Award ’07 for 1st class in madhyamik education.